Sugar acids and derivatives
Medchemexpress LLC 4-methylumbelliferyl-α-D-galactopyranoside | 38597-12-5 | MFCD00063278 | 99.8% | 338.31 g/mol | C16H18O8 | 50 MG
4-Methylumbelliferyl-α-D-galactopyranoside is a blue pro-fluorogenic substrate used to measure α-galactosidase A (GLA) activity. Enzymatic hydrolysis releases galactose and fluorescent 4-methylumbelliferone (4-MU), enabling sensitive fluorometric detection of enzyme activity in biochemical and cell-based assays. Supplied as a high-purity powder for research use only.
- Fluorogenic substrate for α-galactosidase assays
- Releases fluorescent 4-methylumbelliferone upon enzymatic cleavage
- High purity (99.8%) suitable for enzymatic assays
- Supplied as 50 mg powder
- Recommended storage: powder at -20°C to maximize stability
Medchemexpress LLC D-Psicose-d (D-Allulose-d) | 53685-24-8 | 99.9% | 181.16 | 10 MG
D-Psicose-d is a deuterium-labeled form of D-Psicose, which is an orally active rare sugar. D-psicose has been shown to inhibit p38-MAPK phosphorylation and MCP-1 expression, as well as the AGEs/RAGE/NF-κB pathway. It also protects pancreatic β-islets and improves hyperglycemia and non-alcoholic fatty liver disease induced by a high-fat diet. This compound can be utilized as a tracer or an internal standard for quantitative analysis methods such as NMR, GC-MS, or LC-MS. Deuteration, the incorporation of stable heavy isotopes into drug molecules, is used for quantitation during drug development and has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Apexbio Technology LLC Heparin(Synonyms: Heparin Sodium, Unfractionated Heparin, Sodium Heparin, Heparinic Acid, Liquaemin, Calciparine), 100mg, CAS: 9005-49-6.
Heparin (CAS 9005-49-6) is a highly sulfated glycosaminoglycan known primarily for its anticoagulant properties In biological systems it is stored in granules within specific animal tissues and cells potentially serving defensive roles against pathogens In vitro studies demonstrate that Heparin dose-dependently suppresses granulocyte aggregation and degranulation triggered by FMLP or serum-activated zymosan and specifically blocks FMLP-induced superoxide anion production Additionally in rat models Heparin treatment reduces both the binding affinity and density of angiotensin II receptors on adrenal cells resulting in decreased angiotensin II-stimulated aldosterone secretion Heparin is extensively applied in biomedical research to investigate granulocyte-mediated inflammation and renin-angiotensin system signaling
Medchemexpress LLC 4-methylumbelliferyl α-D-galactopyranoside | 38597-12-5 | MFCD00063278 | 99.8% | 338.31 g/mol | C16H18O8 | 1 ML
4-Methylumbelliferyl-α-D-galactopyranoside is a fluorogenic substrate for α-galactosidase that releases 4-methylumbelliferone, producing a fluorescent signal used to measure enzyme activity. The product is supplied as a 10 mM solution in DMSO (1 mL) and is commonly used in biochemical assays and high-throughput screening.
- Supplied as 10 mM in DMSO, 1 mL vial.
- High reported purity (≈99.8%).
- Generates a strong fluorometric signal upon enzymatic cleavage.
- Suitable for α-galactosidase activity assays and screening workflows.
- Available in solution and solid pack sizes for assay flexibility.
Medchemexpress LLC Beta-sitosterol | 83-46-5 | MFCD00003631 | 98.0% | 414.71 g·mol⁻¹ | C29H50O | 10 MG
Beta-sitosterol is a plant-derived phytosterol used as a reference standard and research reagent for studies of cell signaling, inflammation, oxidative stress, and antitumor activity. It is supplied in small quantities suitable for laboratory assays and analytical work.
- Used as a reference standard in biochemical and analytical assays.
- Relevant for studies of inflammation, oxidative stress, and cell signaling.
- High purity provides reproducible experimental results.
- Available in small package sizes suitable for bench-scale experiments.
![Medchemexpress LLC 4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine | 693228-63-6 | MFCD14155805 | 99.1% | 368.46 g·mol⁻¹ | C18H20N6OS | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000241055.png-250.jpg)
Medchemexpress LLC 4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine | 693228-63-6 | MFCD14155805 | 99.1% | 368.46 g·mol⁻¹ | C18H20N6OS | 25 MG
CYC-116 is a small-molecule inhibitor of Aurora A and Aurora B kinases with low-nanomolar inhibitory potency. It is used as a research reagent to investigate mitotic signaling and cell-cycle regulation and is supplied as a purified solid for in vitro studies.
- Potent dual Aurora A and B inhibitor with Ki ≈8-9 nM.
- Suitable for studying mitotic signaling and cell-cycle regulation in vitro.
- High purity (>99.0%) for reliable experimental results.
- Chemical formula C18H20N6OS; molecular weight 368.46 g·mol⁻¹.
- Available in multiple small-quantity pack sizes for laboratory use.
Medchemexpress LLC BET-IN-14 | 2243669-93-2 | C30H37N7O2 | 1 MG
BET-IN-14 is an orally active pan BET inhibitor (IC50: 5.35 nM) exhibiting anti-cancer activity. It shows anti-tumor effects against various cancer cell lines, including MM.1S, Ty-82, MV-4-11, and KG-1 cells, with an average IC50 of 174.7 nM after 72 hours. In vivo, BET-IN-14 inhibits tumor growth in MV-4-11 xenograft models.
- Orally active pan BET inhibitor
- Exhibits anti-cancer activity
- Effective against various cancer cell lines (MM.1S, Ty-82, MV-4-11, KG-1)
- Inhibits tumor growth in xenograft models
Matrix Scientific (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)-tetrahydro-2H-pyran-3,4,5-triyl triacetate, 21085-72-3, MFCD00061613, 1g
Molecular Formula C13H17BrO9, Purity 95+%, Molecular Weight 397.18, Melting Point 106-107°
Medchemexpress LLC Bet bromodomain inhibitor 4 | 2407658-41-5 | ≥98.0% | 518.59 g/mol | C27H31FN8O2 | 10 MG
BET bromodomain inhibitor 4 is a small-molecule inhibitor of BET family bromodomain epigenetic reader domains supplied for research use as a 10 mg powder. It is used in preclinical studies to probe BET-mediated epigenetic regulation and assay bromodomain interactions.
- Inhibits BET bromodomain activity.
- Intended for research use only.
- Supplied as a 10 mg powder for laboratory applications.
- Target: epigenetic reader domain (BET bromodomain).
- CAS number: 2407658-41-5.
- Molecular formula: C27H31FN8O2; molecular weight: 518.59 g/mol.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years).
Medchemexpress LLC Integrin alpha 6 bet 10ug
Integrin alpha 6 beta 1 Protein Human (HEK293 Flag-His) is the recombinant human-derived Integrin alpha 6 beta 1 protein expressed by HEK293 with C-His C-Flag labeled tag has molecular weight of 110 130 kDa respectively
Medchemexpress LLC 4-Methylumbelliferyl β-D-galactopyranoside | 6160-78-7 | MFCD00036773 | 99.1% | 338.31 | 500 MG
4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase. When cleaved, it produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer.
- Fluorescent substrate for β-galactosidase
- Produces a water-soluble blue fluorescent coumarin fluorophore when cleaved
- Detectable using a fluoroenzymeter or fluorometer
- White to off-white solid
- Molecular weight of 338.31
- Purity of 99.06%
- Excitation at 390 nm
- Emission at 480 nm
Medchemexpress LLC 4-methylumbelliferyl α-L-arabinofuranoside | 77471-44-4 | MFCD00057308 | 99.9% | 308.28 | C15H16O7 | 5 MG
4-Methylumbelliferyl α-L-arabinofuranoside is a fluorogenic glycosidase substrate used to measure α-L-arabinofuranosidase activity. Enzymatic hydrolysis releases fluorescent 4-methylumbelliferone, enabling sensitive fluorometric assays in biochemical and enzymology workflows. For research use only.
- Fluorogenic substrate for α-L-arabinofuranosidase assays.
- Produces 4-methylumbelliferone for sensitive fluorometric detection.
- High purity (99.93%) to minimize background signal.
- Molecular weight 308.28 and formula C15H16O7.
- Soluble in DMSO at ≥ 50 mg/mL.
- White to off-white solid with recommended cold storage for stability.
- Supplied in small research pack sizes suitable for assay development.
Medchemexpress LLC 4-methylumbelliferyl β-d-glucopyranoside | 18997-57-4 | MFCD00063694 | 99.9% | 338.31 g/mol | C16H18O8 | 1G
4-Methylumbelliferyl β-D-Glucopyranoside is a fluorogenic β-D-glucoside substrate used to measure β-glucosidase activity. Enzymatic cleavage releases 4-methylumbelliferone (4-MU), a highly fluorescent reporter (emission 445-454 nm); excitation maxima are pH-dependent (330, 370, 385 nm at pH 4.6, 7.4, 10.4). The product is supplied as a solid and as a 10 mM solution in DMSO for convenient assay setup.
- Fluorogenic substrate for β-glucosidase assays.
- Releases 4-methylumbelliferone for sensitive fluorescence detection.
- High reported purity (99.87%).
- Available as solid and 10 mM solution in DMSO.
- Suitable for biochemical and cell-based enzyme activity assays.
- Molecular weight 338.31 g/mol; formula C16H18O8.
- Pack sizes suitable for assay workflows, including 1 g solid options.
Medchemexpress LLC Glucuronic acid sodium | 7182-77-6 | 1 MG
Glucuronic acid sodium is a polysaccharide that exhibits anti-inflammatory activity, supporting the healing of ulcerative colitis. It also enhances the intestinal barrier by upregulating tight junction proteins like ZO-1 and Occludin. Additionally, it modulates gut microbiota by increasing beneficial bacterial populations while suppressing harmful ones.
- Exhibits anti-inflammatory activity
- Supports healing of ulcerative colitis
- Enhances intestinal barrier function
- Modulates gut microbiota
- Increases beneficial bacterial populations
- Suppresses harmful bacterial populations